August 27, 2016

James Otto dispenses advice again:

they even make it in lollipops. china white is every where? I wonder why is it called white ?sense it means SURRENDER? enter the other world ? see you on the other side? your surrounded and you save the last bullet for you? ask why in andy of mayberry the deputy only had one bullet, or him? may day is THE END? you know the seeger tune: where have the flowers gone? we know heroin POPPIES are beautiful flowers… Like WWII berlin, all available cutivation space in the city was planted with POPPIES-flowers!!! harvest time= the comfort of the church?

 

The News article:

There’s been a sharp upswing in fatal overdoses from the painkiller fentanyl in recent years, which the Drug Enforcement Administration says is thanks at least in part to how powerful it is.

A dose of the drug is about 100 times more potent than the same amount of morphine.

SEE MORE: Heroin Might Be The Most Addictive Drug, And It’s A Growing Problem

Certain synthetic versions can be 10,000 times stronger. They’re marketed as elephant tranquilizer — and now they’re finding their way into recreational drugs in the Midwest.

Both fentanyl and morphine act on the same receptors in the brain as a sedative, to suppress pain and to slow down breathing. Like morphine, fentanyl is used to treat severe pain, sometimes during recovery from surgery. So what makes fentanyl so much worse?

It was designed in 1960 explicitly to act faster and be stronger than morphine.

This is thanks to its chemical structure. While morphine is hydrophilic, meaning it dissolves in water, fentanyl is lipophilic, meaning it dissolves in lipids and fats.

The blood-brain barrier naturally keeps out most hydrophilic molecules, but it lets in many lipophilic ones.

Fentanyl is more than 130 times more likely to enter the brain than morphine — so a similar dose can have a much more significant impact.

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